Transport of oxygen

In normoxic conditions, oxygen is transported to tissues combined with hemoglobin. The biochemistry of this binding has been closely studied; and it is well-known that O2/CO2 exchange in both muscle and lung is the result of the differential properties of O2 and CO2 binding to hemoglobin under the influence of the surrounding chemistry. This differential affinity of hemoglobin for O2 and CO2, ensuring O2/CO2 exchange, is responsible for the vital cycle. In fact, under hyperbaric oxygen, hemoglobin being oxygen-saturated, it is as dissolved gas that the extra oxygen reaches tissues.

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