Thus the changes in central haemodynamics induced by HBO therapy (23 ata) include (1) decreased heart rate, (2) increased peripheral resistance which tends to (3) increase arterial blood pressure and (4) maintain or slightly decrease cardiac output. These manifestations seem to be mainly related to the peripheral action of the high pressure of oxygen which have both a direct vasoconstrictive action on the vessels and an indirect action by bringing into play the chemo- and baroreceptors as well as the autonomic (parasympathetic) nervous system.

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