Experimental facts

Most authors agree that cardiac output decreases in HBO. Yet the various available studies report contradictory results: exposure to oxygen at 1 ata decreased cardiac output in rats in Torbati study23. However, this effect was not observed by Onarheim & Tyssebotn24, not by Smith in their work on dogs25, nor by Matalon in their study involving ewes15. Cardiac output even increased when manifestations of oxygen toxicity started to occur. In human beings, however, most authors (Eggers26, Whalen27, Andersen & Hillestad28, Kenmure21) observed a decrease in cardiac output, but amplitude was small (10-15 %) and the physiological significance uncertain.

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