Bacterial invasion

Anaerobic bacteria enter the body under 2 very different circumstances: either (1) by external invasion through direct inoculation or wound contamination by spores or bacteria in soil, or (2) by internal invasion by anaerobic bacteria originating from natural bacterial flora. Whenever the oral, intestinal or genital mucosa is broken, a septic cavity is brought into contact with the submucosal tissue which is normally sterile. Usually local and general immune mechanisms are able to limit bacterial contamination to the point of entry while the break in the mucosa is repaired. In some cases, however, they are overcome and an infection develops on the basis of germ virulence vs host immunocompetence.

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